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In the modern research, we documented the identification as well as the characterization of a brand new atypical opioid receptor with exclusive negative regulatory Homes toward opioid peptides.1 Our success showed that ACKR3/CXCR7, hitherto often called an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is also a broad-spectrum scaven